David Epstein. (Seagen Photo)

— Seattle biotech giant Seagen has appointed a new CEO, David Epstein, a former executive at Novartis. Epstein also joined the company’s board of directors.

Epstein take the helm of the company six months after Seagen co-founder and longtime CEO Clay Siegall resigned from the role in the wake of allegations of domestic abuse and an incident at his home where he was arrested. Siegall, who helped launch Seagen in 1998, has denied the allegations.

Epstein has more than 30 years of experience in the biopharmaceutical industry, including 25 years at Novartis, where he built the company’s oncology business unit up from its from inception, ultimately serving as CEO of Novartis Pharmaceuticals, a division of Novartis AG.

Most recently, Epstein was an executive partner at Flagship Pioneering, the Boston-based venture capital firm that bankrolled Moderna Therapeutics and is known for its hands-on approach to fostering startups.

“David’s demonstrated ability to build and scale a global oncology business, his experience in both large multi-faceted organizations and small biotechnology startups, combined with deep oncology knowledge, provide the strategic and operational expertise needed to lead Seagen to the next level,” said Seagen board chair Felix Baker in a statement Thursday announcing the appointment.

Roger Dansey, who served as the company’s chief medical officer since 2018 and as interim CEO since May, is now president of research and development. He also will continue to serve as chief medical officer. In addition, the company appointed oncologist Sandra Swain, a professor of medicine at Georgetown University Medical Center and vice president of genetic medicine for MedStar Health, to its board of directors.

Seagen was reportedly in talks earlier this year with Merck over a potential acquisition, which reportedly stalled over the price.

Bothell-Wash.-based Seagen employs more than 2,800 people in the Seattle area and its other locations and brought in $510 million in revenue in the third quarter of 2022. The company has four approved cancer therapies on the market, more than two dozen candidates in clinical trials, and announced plans earlier this year to build a new manufacturing facility north of Seattle.

Other key personnel changes across the Pacific Northwest tech industry:

  • Damon Cronkey, previously a partner with XSeed Capital, is now director of corporate development at Amazon.
  • Bellevue, Wash.-based employee well-being technology company Limeade named Dave Smith president and chief operating officer. He was previously general manager of the company’s TINYPulse division. Last year Limeade acquired TINYPulse, where Smith was president and chief operating officer.
  • Volha Hrechka is now venture manager at the Creative Destruction Lab at the University of Washington, leading an advanced manufacturing cohort. She was previously director of business development at Intellectual Ventures.
  • Michael Welch is now vice president of sales at Yesler, the Seattle startup creating an Expedia-like experience for the lumber markets. Welch previously held roles at New Relic, Thales, Verivo, Safenet, and Microvision.
  • Jeff Seacrist is now senior vice president of marketing at consumer data analytics company Lytics. Seacrist was previously vice president of product management at Oracle, which acquired Portland-based Webtrends, where Seacrist was formerly vice president of product management.
Like what you're reading? Subscribe to GeekWire's free newsletters to catch every headline

Job Listings on GeekWork

Find more jobs on GeekWork. Employers, post a job here.