Massachusetts-based Moderna’s share price — and the stock market as a whole — were lifted today by the company’s encouraging report about a coronavirus vaccine trial that got its start at Seattle’s Kaiser Permanente Washington Health Research Institute.

  • In a statement, Moderna said interim results from the Phase 1 clinical trial, which began in mid-March and involved 30 people who received the vaccine known as mRNA-1273, show that the vaccine produced binding antibodies in all recipients and neutralizing antibodies in the first eight recipients for whom data were available. The vaccine was “generally safe and well-tolerated,” with self-resolving adverse effects seen at higher doses, Moderna said.
  • Those are promising signs for the RNA-based vaccine’s ability to fight off the virus, but the Phase 1 trial is still too small to be definitive and not meant to judge efficacy. The vaccine is moving into Phase 2 trials under the Food and Drug Administration’s fast-track guidelines, and Phase 3 trials are due to begin in July.
  • Moderna is already ramping up vaccine production, and if results from later trials show mRNA-1273 is truly safe and effective, it might go into distribution by early next year. That prospect is what drove Moderna’s share price up nearly 20% and the Dow Jones Industrial Average up more than 900 points during today’s trading session.

Update for 4:40 p.m. PT May 18: We’ve updated this report based on today’s closing market prices.

Like what you're reading? Subscribe to GeekWire's free newsletters to catch every headline

Job Listings on GeekWork

Find more jobs on GeekWork. Employers, post a job here.